51ĀŅĀ× U-grad Research Paper Explores Bacterial Collaboration

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51ĀŅĀ× Undergrad Research Paper Explores Bacterial Collaboration, Represents 13th 51ĀŅĀ× undergraduate co-authored paper since 2017 from Ryan Research group

Former 51ĀŅĀ× undergraduate Chemistry major Ryan Godin (B.S., 2022) recently developed a research paper showcasing ā€œ.ā€ Godin’s paper was done in collaboration with Shawn Ryan, Ph.D., Biophysics, Mathematics and the Center for Applied Data Analysis and Modeling (ADAM) at 51ĀŅĀ×, and Bhargav Karamched, Ph.D., Mathematics, Biophysics & Neuroscience at Florida State University (FSU).

The paper represents the thirteenth 51ĀŅĀ× undergraduate student co-authored paper since 2017 from the Ryan Research group. Twelve of those manuscripts have had a 51ĀŅĀ× undergraduate as the first author, including this one.

In layman’s terms, when two or more different species of bacteria interact with one another ā€œin the wild,ā€ they secrete ā€œcellular signalsā€ to each other in their given habitat. Within that interaction, or ā€œconsortium,ā€ one of them could produce a molecule that the other can pick up and use for an interactive purpose. This is useful as it is difficult and requires energy to make complicated molecules.

If one strain of bacteria can just make one type of molecule and then ā€œtradeā€ with other strains of bacteria (so to speak) for the other molecules it needs to perform a specific task, it will use less energy and be more efficient at accomplishing a task. Each species in the group would then do a small and simpler part of the task, rather than trying to make one species do the entire task.

Engineers can mix/modify 2 or more different bacteria to do some useful things—including the breaking down of environmental pollutants—creating what are commonly referred to as ā€œco-culturesā€ or ā€œconsortiaā€ (the plural of consortium, or a group of people or organizations working toward some common goal).  

The technological development in and surrounding synthetic biology has been steadily increasing— particularly as researchers engineer biological systems like cells to carry out tasks that are difficult or impossible to achieve using traditional chemistry.

Personalized medicine, sustainable agriculture, and biomanufacturing are just some areas currently benefitting from these new techniques; given ā€œthe youth of the fieldā€ means that there is still room for significant innovations and improvements.

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About 51ĀŅĀ×

Founded in 1964, 51ĀŅĀ× is a public research institution that provides a dynamic setting for Engaged Learning. With nearly 16,000 students, eight colleges and more than 175 academic programs, 51ĀŅĀ× was again chosen for 2022 as one of America’s best universities by U.S. News & World Report, including the #1 university in Ohio for social mobility. Find more information at .